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Chicago biocompany managed to print a human mini-heart

Printed heart

Specialists of the Chicago biotechnological company BIOLIFE4D successfully printed on a 3D bioprinter a human mini-heart that has the same structure as the full-size one. This is an important step in creating an artificial heart suitable for transplantation.

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The artificial heart was printed by cells received from the patient — cardiomyocytes and bio-ink made from extracellular matrix compounds. BIOLIFE4D first printed cardiac human tissue in June 2018. Later this year, individual components of the heart were printed, including valves, ventricles, and blood vessels.

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This process involves reprogramming the patient’s white blood cells into induced pluripotent stem cells (iPS cells), which can turn into various types of cells, including cardiac.

The ultimate goal of the company is to create a bioprint of a fully functional human heart. Theoretically, 3D grafts can reduce or even completely solve the problem of donor organs. At the same time, BIOLIFE4D is far from the only company leading such developments. Previously, scientists from Tel Aviv University and MIT biotechnologists printed their versions of the artificial heart.

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